Intelligent Vibration Therapy Gloves for Parkinson’s Disease
A wearable neurostimulation glove system powered by the nRF5340 BLE platform, designed to generate programmable vibration stimulation profiles using PWM waveform arrays for Parkinson’s therapy research.
Project Overview
The Intelligent Vibration Therapy Gloves project is an advanced wearable healthcare solution developed to assist individuals affected by Parkinson’s disease through targeted vibration-based stimulation therapy. Built around the Nordic Semiconductor nRF5340 dual-core BLE platform, the system generates specialized vibration stimulation profiles using programmable PWM waveform arrays to deliver highly controlled therapeutic pulse patterns. The device integrates precision-controlled vibration actuators, configurable therapy modes, and low-latency real-time firmware to ensure stable and repeatable stimulation output. By leveraging PWM array sequencing, the platform can reproduce complex vibration signatures with precise timing, intensity modulation, and frequency control, enabling flexible experimentation for neurological stimulation research and assistive therapeutic applications. Bluetooth Low Energy (BLE) connectivity supports wireless configuration, diagnostics, and future mobile integration capabilities. The embedded architecture was optimized for synchronized actuator driving, low-power wearable operation, and scalable firmware expansion while maintaining comfort, portability, and real-time responsiveness for continuous wearable usage.
Challenge
Developing a wearable therapeutic platform capable of generating highly accurate and repeatable vibration stimulation profiles using PWM waveform arrays while maintaining low latency, stable BLE communication, synchronized actuator control, and low power consumption in a compact wearable device.
Solution
Designed a real-time embedded firmware architecture on the nRF5340 BLE SoC utilizing programmable PWM array sequencing for precise waveform-based vibration stimulation. Optimized the firmware for deterministic timing control, synchronized motor actuation, and efficient low-power operation while leveraging the dual-core architecture to separate BLE communication from real-time stimulation processing tasks.
Key Features
Results & Impact
Project Info
Client
N/A
Duration
4 Months
Year
2024
Technologies
Client Success
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ZyntelliTech exceeded our expectations in delivering a custom firmware solution for our IoT distance measurement device. Their team expertly developed firmware on the Nordic nRF9160 platform, integrating a Time-of-Flight (ToF) sensor to measure distance with high precision and consistency. In addition to accurate sensor integration, ZyntelliTech implemented GPS functionality and designed a reliable data pipeline to transmit real-time sensor readings and location data to our AWS cloud infrastructure. Their deep understanding of LTE-M/NB-IoT communication, MQTT protocols, and cloud connectivity enabled seamless, low-latency performance across our system. Throughout the project, ZyntelliTech demonstrated excellent technical skills, clear communication, and a proactive approach to problem-solving. Their firmware was well-structured, power-optimized, and thoroughly documented—making it easy to scale and maintain. We highly recommend them as a development partner for any IoT, cloud-connected, or sensor-driven project.
Hunter Raley, CEO
We partnered with ZyntelliTech Development LLC to develop a custom IoT solution based on the ESP32-S3 platform—and the results were exceptional. Their team engineered a reliable, low-power controller that captures real-time UV sensor data and seamlessly transmits it to our AWS cloud infrastructure. ZyntelliTech handled every layer of the system: from embedded firmware with OTA update capabilities and AWS IoT Core fleet provisioning, to full mobile app development using Flutter. The mobile apps allow users to monitor and manage devices effortlessly, with real-time data visualization and secure device onboarding. Their ability to deliver a tightly integrated solution—from hardware to cloud to mobile—was exactly what we needed. The firmware was efficient, the cloud communication was rock-solid, and the apps were beautifully designed and intuitive. ZyntelliTech proved to be a reliable and forward-thinking development partner, and we highly recommend them for any end-to-end IoT project.
Charles Rigby, CEO
ZyntelliTech Development LLC delivered a complete RF control solution for our vehicle system, handling both hardware and firmware development with precision and professionalism. Their team designed custom electronic boards for the RF transmitter and receiver modules, ensuring reliable long-range communication and signal integrity under demanding conditions. In addition to hardware design, ZyntelliTech developed embedded firmware optimized for responsive control, robust pairing, and interference resistance. The system performed flawlessly in field tests, demonstrating the team's deep understanding of RF communication protocols and automotive-grade reliability. This project showcased ZyntelliTech’s end-to-end capability—from schematic and PCB design to low-level embedded programming and RF performance tuning. We highly recommend them for any project requiring custom wireless control systems or vehicle integration.
Dennis Chim, Co-Founder
ZyntelliTech Development LLC played a pivotal role in the successful development of our advanced wireless sensor system. The team engineered a scalable solution using Nordic’s nRF52 series for BLE mesh networking and the nRF9160 as a cellular gateway, seamlessly connecting edge devices to our AWS cloud infrastructure. ZyntelliTech provided full-stack services—including custom PCB design, low-power firmware development, and end-to-end AWS integration. Their implementation of a robust BLE mesh network enabled reliable, long-range communication between sensor nodes, while the nRF9160 gateway ensured real-time data transmission over LTE-M with secure cloud connectivity. In addition to the technical architecture, they managed prototype manufacturing and hardware validation, delivering a complete, production-ready system. Their deep expertise in embedded systems, wireless communication, and cloud-connected IoT made them an invaluable partner. We highly recommend ZyntelliTech for complex IoT product development and deployment.
